Potential risk factors for diabetes mellitus type 1

Diabetes mellitus type 1 (T1D) develops as a result of the interaction genetic and environmental factors. Genetic predisposition to T1D turns into clinical reality only in half hereditary cases, which indirectly indicates importance external factors, significance is periodically reviewed. Retrospective prospective foreign national studies were included. PubMed, Medline eLibrary searched. Modern ideas about possible impact main prenatal postnatal factors on development autoimmune response against insulin-producing islet cells discussed. The risk developing diabetes determined by complex predisposition. mechanisms their influence remain rather unknown. Further research needed determine strategies primary secondary prevention T1D.